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DOI: 10.1097/01.CCM.0000025908.95498.A3 28

While sensory attributes such as taste, odor, color, and aroma hinder consumer acceptance, new technologies such as microencapsulation, fermentation, and enzymatic processing offer promising results in mitigating these disadvantages (131)

Decreased SIRT1 expression in the cortex is closely associated with the accumulation of both A and Tau in AD patients (133), aberrant nuclearcytoplasmic localization of H3K4me3 has also been reported in early-stage AD (134)

These drugs are labeled as class 1 ferroptosis inducers, and those targeting GPX4 activity are considered class 2 ferroptosis inducers

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for example, when hepatocytes secrete GSH, another cell can hydrolyze it in its precursors (cysteinyl-glycine and glutamate) by -glutamyl-transpeptidase (-GT, EC 2.3.2.2) that are expressed on the outer plasma membrane